All functions

AnnotateResults()

Annotate coMethDMR Pipeline Results

betaMatrix_ex1

Alzheimer's Prefrontal Cortex (PFC) Methylation Data

betaMatrix_ex2

Alzheimer's Prefrontal Cortex (PFC) Methylation Data

betaMatrix_ex3

Alzheimer's Prefrontal Cortex (PFC) Methylation Data

betaMatrix_ex4

Alzheimer's Prefrontal Cortex (PFC) Methylation Data

betasChr22_df

Prefrontal Cortex (PFC) Methylation Data from Alzheimer's Disease subjects

CloseBySingleRegion()

Extract clusters of CpGs located closely in a genomic region.

CoMethAllRegions()

Extract contiguous co-methylated genomic regions from a list of pre-defined genomic regions

CoMethSingleRegion()

Wrapper function to find contiguous and comethyalted sub-regions within a pre-defined genomic region

CpGsInfoAllRegions()

Test Associations Between Regions and Phenotype

CpGsInfoOneRegion()

Test Associations Between a Region and Phenotype

CreateParallelWorkers()

Create a Parallel Computing Cluster

CreateRdrop()

Computes leave-one-out correlations (rDrop) for each CpG

FindComethylatedRegions()

Find Contiguous Co-Methylated Regions

GetCpGsInRegion()

Extract probe IDs for CpGs located in a genomic region

GetResiduals()

Get Linear Model Residuals

ImportSesameData()

Import Illumina manifests (sesameData versions)

lmmTest()

Fit mixed model to methylation values in one genomic region

lmmTestAllRegions()

Linear Mixed Models by Region

MarkComethylatedCpGs()

Mark CpGs in contiguous and co-methylated region

MarkMissing()

Return Column and Row Names of Samples and Probes under the Missingness Theshold

NameRegion()

Name a region with several CpGs based on its genomic location

OrderCpGsByLocation()

Order CpGs by genomic location

pheno_df

Example phenotype data file from Prefrontal Cortex (PFC) Methylation Data of Alzheimer's Disease subjects

RegionsToRanges()

Convert genomic regions in a data frame to GRanges format

WriteCloseByAllRegions()

Extract clusters of CpG probes located closely